Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060332 | 1.00 | MET (0.44) | METIP6K1MAPK14NPC1RAB9A | |
| SCHEMBL5336499 | 0.87 | GLA (0.42) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5336504 | 0.87 | GLA (0.42) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5334880 | 0.78 | GLA (0.39) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5334885 | 0.78 | GLA (0.39) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5333926 | 0.76 | CYSLTR1 (0.39) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5337396 | 0.76 | CYSLTR1 (0.39) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5337401 | 0.76 | CYSLTR1 (0.39) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5333921 | 0.76 | CYSLTR1 (0.39) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5335307 | 0.72 | CYSLTR1 (0.37) | NPC1RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |