SCHEMBL406053

SCHEMBL406053

NNC(=O)c1ccccc1Br

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA9 Q16790 1/20 0.58
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
CTSD P07339 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
POLB P06746 2/20 0.51
HPGD P15428 2/20 0.51
HTT P42858 1/20 0.51
NLRP3 Q96P20 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239328 0.84 CTSD (0.63) CA1CA2CA9CTSDMEN1
SCHEMBL30547074 0.84 CTSD (0.63) CA1CA2CA9CTSDMEN1
SCHEMBL2722234 0.83 CA1 (0.50) CA1CA2CA9NPC1RAB9A
SCHEMBL28640185 0.82 SMN1; SMN2 (0.61) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL15103340 0.82 SMN1; SMN2 (0.61) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL21625558 0.82 CA1 (0.49) CA1CA2CA9NPC1RAB9A
SCHEMBL30015441 0.82 CA1 (0.49) CA1CA2CA9NPC1RAB9A
Hydrazine SCHEMBL14300720 0.81 CTSD (0.61) CA1CA2CA9CTSDMEN1
Hydrochloric Acid SCHEMBL6692325 0.81 CTSD (0.61) CA1CA2CA9CTSDMEN1
Hydroxyamine SCHEMBL14300671 0.81 CTSD (0.61) CA1CA2CA9CTSDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113698407-B Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction 武汉科技大学 2022-11-29 CN claimed
CN-113698407-A Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction 武汉科技大学 2021-11-26 CN claimed
CN-109232463-A Using DMF as one step of carbon source construct 2-(4- bromophenyl) -1,3,4- oxadiazoles method 桂林理工大学 2019-01-18 CN claimed
CN-106397420-B 3- (5- aryl-1,3,4-oxdiazole -2- bases) asarinin analog derivative, preparation method and application 郑州大学 2018-10-09 CN claimed
CN-108003178-A Acylhydrazone copper (II) complex and preparation method thereof and its application in urease activity is suppressed 辽宁师范大学 2018-05-08 CN claimed
CN-105669491-B A kind of acylation method of amine 苏州大学 2017-10-13 CN claimed
CN-106749392-A The application of acylhydrazone vanadium complex and preparation method thereof and acylhydrazone vanadium complex in catalytic epoxidation 辽宁师范大学 2017-05-31 CN claimed
CN-106397420-A 3-(5-aryl-1,3-4-oxadiazole-2-yl)sarisan derivatives, and preparation method and application thereof 郑州大学 2017-02-15 CN claimed
CN-105669491-A Acidylation method of amine 苏州大学 2016-06-15 CN claimed
CN-102875542-B Oxadiazole group-containing red-light emitting iridium complex, and preparation method and use thereof NANJING UNIVERSITY OF TECHNOLOGY 2015-07-01 CN claimed
US-4816414-A CONTROLLED FORMATION AND GROWTH OF OPTICALLY VISIBLE CRYSTALS CRYSTAL DIAGNOSTICS, INC. (US) 1989-03-28 US claimed
EP-0140886-B1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS Crystal Diagnostic Systems, Inc. (US) 1988-09-07 EP claimed
EP-0140886-A4 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-09-02 EP claimed
EP-0140886-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-05-15 EP claimed
WO-1984004165-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS LITTLE INC A (US) 1984-10-25 WO claimed
US-4380587-A Film badge for determining carbonyl compounds ARTHUR D. LITTLE, INC. (US) 1983-04-19 US claimed
EP-4653436-A1 HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF GUANGZHOU YUFAN NANTU BIOTECHNOLOGIES CO., LTD (CN) 2025-11-26 EP disclosed
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF SCHRÖDINGER, INC. 2025-08-21 US disclosed
US-4166129-A AGRICULTURAL AND HORTICULTURAL N-BENZOYL-N'-TRICHLOROETHYLIDENE HYDRAZINE FUNGICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1979-08-28 US disclosed
US-4093812-A MICROBIOCIDES, DISINFECTANTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC CA1 4882/4885CA2 4759/4885CA9 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.