Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.49 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678793 | 0.86 | SMN1; SMN2 (0.46) | PPARDPPARGPPARASMN1; SMN2HPGD | |
| SCHEMBL4061841 | 0.82 | PPARD (0.55) | PPARDPPARGPPARACYP3A4 | |
| SCHEMBL4061597 | 0.80 | PPARD (0.61) | PPARDPPARGPPARASMN1; SMN2CYP3A4 | |
| SCHEMBL4062758 | 0.78 | PPARG (0.53) | PPARDPPARGPPARACYP3A4 | |
| SCHEMBL4066110 | 0.78 | PPARG (0.55) | PPARDPPARGPPARACYP3A4 | |
| SCHEMBL4067797 | 0.76 | PPARD (0.48) | PPARDPPARGPPARACYP3A4MEN1 | |
| SCHEMBL4064895 | 0.76 | PPARD (0.60) | PPARDPPARGPPARACYP3A4 | |
| SCHEMBL10220166 | 0.75 | PPARD (0.78) | PPARDPPARGPPARACYP3A4 | |
| SCHEMBL4055838 | 0.75 | PPARD (0.49) | PPARDPPARGPPARAKDM4ECYP3A4 | |
| SCHEMBL4064821 | 0.74 | PPARD (0.54) | PPARDPPARGPPARACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666472-B1 | PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | ONO PHARMACEUTICAL CO (JP) | 2012-08-01 | — | — | EP | disclosed |
| US-7560475-B2 | Phenylacetic acid derivative, process for producing the same, and use | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| US-20070105868-A1 | Phenylacetic acid derivative, process for producing the same, and use | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1666472-A1 | PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105868-A1 | Phenylacetic acid derivative, process for producing the same, and use | PPARA, PPARD, PPARG | PPARD 2/4885PPARG 3/4885PPARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.