SCHEMBL4064895

SCHEMBL4064895

Cc1ccc(CC(=O)O)cc1OCCc1nc(N2CCC(c3ccc(Cl)cc3)CC2)sc1C

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 19/20 0.60
PPARG P37231 18/20 0.60
PPARA Q07869 13/20 0.60
CYP3A4 P08684 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4062758 0.93 PPARG (0.53) PPARDPPARGPPARACYP3A4
SCHEMBL4066110 0.93 PPARG (0.55) PPARDPPARGPPARACYP3A4
SCHEMBL4061597 0.88 PPARD (0.61) PPARDPPARGPPARACYP3A4
SCHEMBL4061841 0.82 PPARD (0.55) PPARDPPARGPPARACYP3A4
SCHEMBL4067797 0.77 PPARD (0.48) PPARDPPARGPPARACYP3A4
SCHEMBL4055838 0.76 PPARD (0.49) PPARDPPARGPPARACYP3A4
SCHEMBL4060544 0.76 PPARD (0.49) PPARDPPARGPPARACYP3A4
SCHEMBL4064821 0.75 PPARD (0.54) PPARDPPARGPPARACYP3A4
SCHEMBL334320 0.75 PPARD (1.00) PPARDPPARGPPARACYP3A4
SCHEMBL4064791 0.75 PPARG (0.39) PPARDPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666472-B1 PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE ONO PHARMACEUTICAL CO (JP) 2012-08-01 EP disclosed
US-7560475-B2 Phenylacetic acid derivative, process for producing the same, and use ONO PHARMACEUTICAL CO., LTD. (JP) 2009-07-14 US disclosed
US-20070105868-A1 Phenylacetic acid derivative, process for producing the same, and use ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-10 US disclosed
EP-1666472-A1 PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105868-A1 Phenylacetic acid derivative, process for producing the same, and use PPARA, PPARD, PPARG PPARD 2/4885PPARG 3/4885PPARA 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.