Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531216 | 0.78 | CYP19A1 (0.38) | MAPTGAAMEN1KMT2A | |
| SCHEMBL11734011 | 0.76 | ALDH1A1 (0.34) | MAPTGAAHPGDMEN1KMT2A | |
| SCHEMBL1637757 | 0.76 | TSHR (0.39) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4922723 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL4926647 | 0.76 | ATM (0.34) | — | |
| SCHEMBL28195381 | 0.72 | ERN1 (0.37) | MEN1KMT2A | |
| SCHEMBL6304840 | 0.71 | MAPT (0.43) | MAPTGAAHPGDMEN1KMT2A | |
| SCHEMBL11724286 | 0.68 | TSHR (0.39) | MEN1KMT2A | |
| SCHEMBL447325 | 0.67 | — | — | |
| SCHEMBL11750501 | 0.67 | ERN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594047-B1 | Arylazo chromoionophores | BAYER AG (US) | 2000-01-05 | — | — | EP | claimed |
| US-5310888-A | Calcium detection | MILES INC. (US) | 1994-05-10 | — | — | US | claimed |
| EP-0594047-A1 | Arylazo chromoionophores | Bayer Corporation (US) | 1994-04-27 | — | — | EP | claimed |
| EP-0122109-A2 | Preparation of cyano- or aminoalkyl substituted aromatic amines | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-10-17 | — | — | EP | claimed |
| CN-118302427-A | Fused ring derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2024099441-A1 | BROMODOMAIN AND EXTRA-TERMINAL (BET) PROTEIN DEGRADER | JINGRUI BIOPHARMA (SHANDONG) CO., LTD. (CN) | 2024-05-16 | — | — | WO | disclosed |
| EP-4281451-A1 | TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS | Jingrui Biopharma Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| EP-3814352-A1 | TRICYCLIC COMPOUNDS | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2021-05-05 | — | — | EP | disclosed |
| EP-3784671-A1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRad Therapeutics, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |
| WO-2019201283-A1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRAD THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |
| CN-101243068-B | Compounds for the treatment of multi-drug resistant bacterial infections | ASTRAZENECA AB | 2012-08-08 | — | — | CN | disclosed |
| EP-1658289-B1 | 3-SUBSTITUTED IMIDAZOPYRIDINE-DERIVATIVES AS C-KIT INHIBITORS | OSI PHARM INC (US) | 2009-03-18 | — | — | EP | disclosed |
| CN-101243068-A | Compounds for the treatment of multi-drug resistant bacterial infections | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | disclosed |
| EP-1041447-A1 | Decolorable image forming material and decoloring method of the same | Kabushiki Kaisha Toshiba (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-0594047-B1 | Arylazo chromoionophores | BAYER AG (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5310888-A | Calcium detection | MILES INC. (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0594047-A1 | Arylazo chromoionophores | Bayer Corporation (US) | 1994-04-27 | — | — | EP | disclosed |
| EP-0122109-A2 | Preparation of cyano- or aminoalkyl substituted aromatic amines | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-10-17 | — | — | EP | disclosed |