Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230838 | 0.82 | NPC1 (0.57) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL28443608 | 0.81 | RAB9A (0.80) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL524926 | 0.81 | RAB9A (0.61) | NPC1RAB9ALMNAKDM4EPKM | |
| Lithium SCHEMBL30618810 | 0.80 | NPC1 (0.55) | NPC1RAB9ALMNAKDM4EPKM | |
| Ammonia Solution, Strong SCHEMBL29096034 | 0.80 | NPC1 (0.55) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL31364411 | 0.80 | NPC1 (0.55) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL30128765 | 0.78 | RAB9A (0.53) | NPC1RAB9ALMNAKDM4EPKM | |
| Formaldehyde SCHEMBL2137330 | 0.78 | NPC1 (0.53) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL1163115 | 0.77 | RAB9A (0.57) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL108424 | 0.77 | RAB9A (0.57) | NPC1RAB9ALMNAKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547751-B2 | Process for the preparation of a polyolefin | DSM IP ASSETS B.V. (NL) | 2009-06-16 | — | — | US | disclosed |
| US-20080153999-A1 | Polymerization of at least one aliphatic or aromatic hydrocarbyl C2-20 mono- or multiolefin in the presence of a catalyst and a boron comprising co-catalyst, wherein the catalyst comprises of a metal-organic reagent, a spectator ligand and optionally at least one equivalent of a hydrocarbylting agent | ARLANXEO NETHERLANDS B.V. (NL) | 2008-06-26 | — | — | US | disclosed |
| EP-1651690-A2 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN | DSM IP Assets B.V. (NL) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005014674-A2 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN | DSM IP ASSETS B.V. (NL) | 2005-02-17 | — | — | WO | disclosed |