Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.60 |
| ▸ | HMGCR | P04035 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9551566 | 1.00 | PTPN7 (0.60) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL31682050 | 1.00 | PTPN7 (0.60) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL22029362 | 1.00 | PTPN7 (0.60) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL4063611 | 1.00 | PTPN7 (0.60) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL31682065 | 1.00 | PTPN7 (0.60) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL710828 | 0.98 | PTPN7 (0.57) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL7315206 | 0.92 | PTPN7 (0.50) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL6272882 | 0.83 | EPHX2 (0.38) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL21099048 | 0.82 | HMGCR (0.43) | PTPN7HMGCRTDP1MAPTRECQL | |
| SCHEMBL9262800 | 0.82 | PAOX (0.40) | PTPN7HMGCRTDP1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059496-A1 | ACETYLENIC COMPOUNDS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008031157-A1 | ACETYLENIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-03-20 | — | — | WO | disclosed |
| EP-0525479-B1 | Spicamycin derivatives and the use thereof | KIRIN BREWERY (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5631238-A | ANTICARCINOGENIC AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5461036-A | Treating colon, gastric, esophageal cancer | KIRIN BEER KABUSHIKI KAISHA (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0525479-A1 | Spicamycin derivatives and the use thereof | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |