Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.72 |
| ▸ | MMP13 | P45452 | 1/20 | 0.72 |
| ▸ | CTSD | P07339 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MYC | P01106 | 1/20 | 0.61 |
| ▸ | MAX | P61244 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.60 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975036 | 0.98 | MMP3 (0.75) | MMP3MMP13CTSDHPGDCISD1 | |
| SCHEMBL7975038 | 0.98 | MMP3 (0.75) | MMP3MMP13CTSDHPGDCISD1 | |
| SCHEMBL8310047 | 0.93 | PIM1 (0.68) | MMP3MMP13HPGDCISD1NPC1 | |
| SCHEMBL4049839 | 0.93 | MMP3 (0.71) | MMP3MMP13CTSDHPGDNPC1 | |
| SCHEMBL4053583 | 0.93 | MMP3 (0.71) | MMP3MMP13CTSDHPGDNPC1 | |
| SCHEMBL13846898 | 0.92 | PIM1 (0.67) | MMP3MMP13CISD1NPC1RAB9A | |
| SCHEMBL7968931 | 0.92 | MMP3 (0.69) | MMP3MMP13CTSDHPGDNPC1 | |
| SCHEMBL7968927 | 0.92 | MMP3 (0.69) | MMP3MMP13CTSDHPGDNPC1 | |
| SCHEMBL7968122 | 0.91 | MMP3 (0.72) | MMP3MMP13CTSDHPGDNPC1 | |
| SCHEMBL7968119 | 0.91 | MMP3 (0.72) | MMP3MMP13CTSDHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |