⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670611 | 0.86 | — | — | |
| SCHEMBL1380254 | 0.79 | — | — | |
| SCHEMBL1101400 | 0.77 | — | — | |
| SCHEMBL8053410 | 0.75 | — | — | |
| SCHEMBL310712 | 0.75 | — | — | |
| SCHEMBL7831444 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL29471655 | 0.75 | — | — | |
| SCHEMBL8801365 | 0.73 | — | — | |
| SCHEMBL16621831 | 0.70 | — | — | |
| SCHEMBL22536958 | 0.70 | RIPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304403-B2 | Heterocyclic CETP inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-06 | — | — | US | claimed |
| EP-1515724-B1 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2009-10-21 | — | — | EP | claimed |
| EP-0194525-B1 | N-CARBAMOYL-AZOLES AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1988-08-10 | — | — | EP | claimed |
| US-4167624-A | 5-Hydroxy-PGI1 pyrrolinylamides | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | claimed |
| US-4138549-A | Inter-phenylene-PG pyrrolinylamides | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | claimed |
| US-4129725-A | 9-Deoxy-9-methylene-PGF1 -pyrrolinylamides | THE UPJOHN COMPANY (US) | 1978-12-12 | — | — | US | claimed |
| CN-112142731-B | 2, 4-disubstituted pyrimidine derivative and preparation method and application thereof | 成都赜灵生物医药科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114671920-A | Amide penta-acetyl geniposide derivative and preparation method and application thereof | 山东省农业科学院 | 2022-06-28 | — | — | CN | disclosed |
| US-20210198218-A1 | COMPOUNDS FOR THERAPEUTIC USE | DART NEUROSCIENCE LLC (US) | 2021-07-01 | — | — | US | disclosed |
| EP-3507277-B1 | HYDROXYNORKETAMINE DERIVATIVES FOR THE TREATMENT OF DISORDERS | DART NEUROSCIENCE LLC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3507277-A1 | HYDROXYNORKETAMINE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | Dart NeuroScience LLC (US) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018044896-A1 | HYDROXYNORKETAMINE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | DART NEUROSCIENCE, LLC (US) | 2018-03-08 | — | — | WO | disclosed |
| US-9676686-B2 | Liquid crystal composition containing nitrogen-containing cyclic compound and liquid crystal display device | JNC CORPORATION (JP) | 2017-06-13 | — | — | US | disclosed |
| US-4118584-A | 9-Deoxy-9-methylene-16-phenyl-PGF compounds | THE UPJOHN COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4110532-A | PROSTAGLANDINS, SMOOTH MUSCLE STIMULANTS | THE UPJOHN COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4098805-A | 9-DEOXY-9-METHYLENE-PGF-TYPE AMIDES | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |