Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TAS2R46 | P59540 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29694449 | 0.63 | ATM (0.67) | RECQLCYP3A4ATMTAS2R46CYP19A1 | |
| SCHEMBL29573092 | 0.54 | RECQL (1.00) | RECQLCYP3A4ATMTAS2R46CYP19A1 | |
| SCHEMBL22139573 | 0.54 | RECQL (1.00) | RECQLCYP3A4ATMTAS2R46CYP19A1 | |
| SCHEMBL29350406 | 0.54 | RECQL (1.00) | RECQLCYP3A4ATMTAS2R46CYP19A1 | |
| SCHEMBL2950607 | 0.54 | NPC1 (0.36) | MAPT | |
| SCHEMBL23007994 | 0.54 | ICAM1 (0.44) | RECQLCYP3A4ATMTAS2R46CYP19A1 | |
| SCHEMBL21475315 | 0.54 | ICAM1 (0.44) | RECQLCYP3A4ATMTAS2R46CYP19A1 | |
| SCHEMBL21475309 | 0.54 | ICAM1 (0.44) | RECQLCYP3A4ATMTAS2R46CYP19A1 | |
| SCHEMBL30978205 | 0.53 | CYP2D6 (0.32) | CYP3A4CYP19A1 | |
| SCHEMBL21475414 | 0.53 | RECQL (0.41) | RECQLCYP3A4ATMTAS2R46CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122447-A1 | SEMI-SYNTHETIC SESQUITERPENE LACTONE PARTHENIN COMPOUND USEFUL FOR CYTOTOXICITY AGAINST CANCER CELL LINES AND ANTICANDER AGENT | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-10-08 | — | — | WO | claimed |
| WO-2009122447-A1 | SEMI-SYNTHETIC SESQUITERPENE LACTONE PARTHENIN COMPOUND USEFUL FOR CYTOTOXICITY AGAINST CANCER CELL LINES AND ANTICANDER AGENT | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-10-08 | — | — | WO | disclosed |