Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.72 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.72 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.72 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683735 | 0.90 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL678960 | 0.84 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL9148374 | 0.79 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DF2 | |
| SCHEMBL7369768 | 0.79 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL7153812 | 0.78 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8686439 | 0.78 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DLPAR1 | |
| SCHEMBL7376634 | 0.76 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9595433 | 0.76 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DPTGER1 | |
| SCHEMBL8684095 | 0.74 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DLPAR1 | |
| SCHEMBL3413842 | 0.74 | CD274 (0.49) | PTGER1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026813-A2 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | Braincells, Inc. (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007134077-A2 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |