SCHEMBL406262

SCHEMBL406262

CCCCCCCCC[Al](CC)CC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
DNM1 Q05193 7/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4435485 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1240788 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9854437 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9067472 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL27535151 0.97 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL969291 0.97 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9854440 0.94 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6053526 0.94 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6053749 0.94 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9506031 0.91 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392615-B1 POLYOLEFIN RESIN COMPOSITION ADEKA CORP (JP) 2016-12-21 EP disclosed
CN-102652142-B Polymerization process in the presence of an antistatic agent BASELL POLYOLEFINE GMBH 2014-05-28 CN disclosed
CN-102482367-B Method for recycling of phenolic antioxidant agent, process for production of olefin polymer, polyolefin powder, and fibers ADEKA CORP 2014-05-07 CN disclosed
CN-102652142-A Polymerization process in the presence of an antistatic agent BASELL POLYOLEFINE GMBH 2012-08-29 CN disclosed
CN-102482367-A Method for regenerating phenol antioxidant, method for producing olefin polymer, polyolefin powder, and fiber ADEKA CORP 2012-05-30 CN disclosed
US-20120022212-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-01-26 US disclosed
CN-102300919-A Polyolefin resin composition for food/medical/water pipe applications 2011-12-28 CN disclosed
CN-102300918-A Polyolefin resin composition 2011-12-28 CN disclosed
EP-2392615-A1 POLYOLEFIN RESIN COMPOSITION Adeka Corporation (JP) 2011-12-07 EP disclosed
US-20110288216-A1 POLYOLEFIN-BASED RESIN COMPOSITION FOR FOOD, MEDICAL, AND MUNICIPAL WATER PIPE APPLICATIONS ADEKA CORPORATION (JP) 2011-11-24 US disclosed
CN-1238359-C Mixed metal alkoxide complexes and polymerization catalysts prepared therefrom UNION CARBIDE CHEM PLASTIC (US) 2006-01-25 CN disclosed
EP-0336593-B2 Method for preparing a supported metallocene alumoxane catalyst EXXON CHEMICAL PATENTS INC (US) 1999-02-03 EP disclosed
US-5147949-A Coordination catalyst for polymerization of alpha-olefins EXXON CHEMICAL PATENTS INC. (US) 1992-09-15 US disclosed
US-5086025-A Polymerization of alpha-olefins using coordination catalyst EXXON CHEMICAL PATENTS INC. (US) 1992-02-04 US disclosed
US-5008228-A Method for preparing a silica gel supported metallocene-alumoxane catalyst EXXON CHEMICAL PATENTS INC. (US) 1991-04-16 US disclosed
EP-0336593-A1 Method for preparing a supported metallocene alumoxane catalyst EXXON CHEMICAL PATENTS INC. (US) 1989-10-11 EP disclosed
WO-1989009237-A1 METHOD OF PREPARING A SILICA GEL SUPPORTED METALLOCENE ALUMOXANE CATALYST EXXON CHEMICAL PATENTS, INC. (US) 1989-10-05 WO disclosed