SCHEMBL4435485

SCHEMBL4435485

CCCCCC[Al](CC)CC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
DNM1 Q05193 7/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1240788 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL406262 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9854437 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9067472 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL27535151 0.97 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL969291 0.97 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9854440 0.94 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6053526 0.94 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6053749 0.94 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9506031 0.91 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7601664-B2 Olefin polymerization catalyst compositions and method of preparation UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2009-10-13 US disclosed
EP-1232161-B1 MIXED METAL ALKOXIDE COMPLEXES AND POLYMERIZATION CATALYSTS MADE THEREFROM UNION CARBIDE CHEM PLASTIC (US) 2007-11-28 EP disclosed
US-7122691-B2 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-17 US disclosed
EP-1196454-B1 MAGNESIUM/TITANIUM ALKOXIDE COMPLEXES AND POLYMERIZATION CATALYSTS MADE THEREFROM UNION CARBIDE CHEM PLASTIC (US) 2005-11-16 EP disclosed
CN-1680394-A Process for producing compound, catalyst component, process for producing catalyst, and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2005-10-12 CN disclosed
US-20050222351-A1 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-10-06 US disclosed
EP-1196461-B1 METHODS OF MAKING MAGNESIUM/TRANSITION METAL ALKOXIDE COMPLEXES AND POLYMERIZATION CATALYSTS MADE THEREFROM UNION CARBIDE CHEM PLASTIC (US) 2005-05-04 EP disclosed
US-20050003953-A1 Olefin polymerization catalyst compositions and method of preparation W. R. GRACE & CO.-CONN. 2005-01-06 US disclosed
CN-1177868-C Magnesium/titanium alkoxid complexes and polymerization catalysts made therefrom ����̼���ﻯѧ�����ϼ�����˾ 2004-12-01 CN disclosed
US-6759362-B2 SOLID COMPLEX CATALYST PRECURSOR THAT FORMS A PROCATALYST WHEN CONTACTED WITH A HALOGENATING AGENT AND OPTIONALLY AN ELECTRON DONOR; PROCATALYST IS CONVERTED TO AN OLEFIN POLYMERIZATION CATALYST BY CONTACTING WITH A COCATALYST UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2004-07-06 US disclosed
US-5151399-A Magnesium, a titanium tetraalkoxide, a alkyl borate ester and an alkanol SHELL OIL COMPANY (US) 1992-09-29 US disclosed
US-5146028-A Selective catalyst, high bulk density polymer SHELL OIL COMPANY (US) 1992-09-08 US disclosed
US-5141910-A Magnesium titanium complex alkoxide catalyst precursor SHELL OIL COMPANY (US) 1992-08-25 US disclosed
US-5132263-A Polymerization catalysts of magnesium alkoxide, titanium tetraalkoxide and phenolic compounds as coordination catalysts SHELL OIL COMPANY (US) 1992-07-21 US disclosed
US-5124298-A Procatalyst of magnesium alkoxide, titanium tetraalkoxide, titanium halide, and phenolic compound; cocatalyst; selectivity control agent SHELL OIL COMPANY (US) 1992-06-23 US disclosed
EP-0481749-A2 Olefin polymerization catalyst SHELL OIL COMPANY (US) 1992-04-22 EP disclosed
US-5106806-A Precursor solution containing complex magnesium and titanium alkoxide, phenolic compound SHELL OIL COMPANY (US) 1992-04-21 US disclosed
US-5082907-A Coordination catalysts SHELL OIL COMPANY (US) 1992-01-21 US disclosed
US-5077357-A Titanium procatalyst and organoaluminum cocatalyst SHELL OIL COMPANY (US) 1991-12-31 US disclosed
US-5066737-A Complex Titanium-Magnesium Procatalyst, Organoaluminum Cocatalyst And A Selectivity Control Agent SHELL OIL COMPANY (US) 1991-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222351-A1 Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer CCNT1, C5, C9 TSHR 4243/4885THRB 3963/4885DNM1 3564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.