SCHEMBL4063145

SCHEMBL4063145

Ic1ccc2n[c]cn2c1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5982381 0.75 NPC1 (0.44) APP
SCHEMBL25045602 0.65 APP (0.49) APP
SCHEMBL5250334 0.64 DNMT1 (0.46) APP
SCHEMBL3138257 0.62 PIK3CG (0.60) APP
SCHEMBL15066606 0.62
SCHEMBL7988504 0.62 APP (0.50) APP
Hydrochloric Acid SCHEMBL2533130 0.62 DYRK1A (0.52) APP
SCHEMBL15177306 0.60 APP (0.73) APP
SCHEMBL17810233 0.59 APP (0.46) APP
SCHEMBL5773449 0.59 APP (0.43) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2040703-B1 DERIVATIVES OF 2-BENZOYL-IMIDAZOPYRIDINES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2009-10-21 EP claimed