Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 7/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733596 | 0.98 | FBP1 (0.52) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL2039575 | 0.98 | FBP1 (0.52) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL27944886 | 0.98 | FBP1 (0.52) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL1960442 | 0.98 | FBP1 (0.52) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL2034620 | 0.98 | FBP1 (0.52) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL3699523 | 0.98 | FBP1 (0.52) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL1958580 | 0.98 | FBP1 (0.52) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL8733615 | 0.89 | FBP1 (0.48) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL10427537 | 0.87 | FBP1 (0.47) | FBP1CYP2C9CYP2C19ALDH1A1AKT1 | |
| SCHEMBL28686815 | 0.81 | FBP1 (0.47) | FBP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109657-A1 | LUBRICATING OIL COMPOSITION | Showa Shell Sekiyu K. K. (JP) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008095966-A1 | LUBRICATING OIL COMPOSITION | SHOWA SHELL SEKIYU K.K. (JP) | 2008-08-14 | — | — | WO | disclosed |