Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | ACR | P10323 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176304 | 0.87 | MAPT (0.48) | L3MBTL1NPSR1ACRMAPTALDH1A1 | |
| SCHEMBL20507301 | 0.84 | MAPT (0.46) | L3MBTL1NPSR1ACRMAPTALDH1A1 | |
| SCHEMBL1456889 | 0.81 | F10 (0.56) | L3MBTL1NPSR1ALDH1A1KDM4EHPGD | |
| SCHEMBL4069525 | 0.80 | NPSR1 (0.54) | L3MBTL1NPSR1MAPTALDH1A1KDM4E | |
| SCHEMBL1456447 | 0.79 | F10 (0.46) | L3MBTL1NPSR1ALDH1A1KDM4EHPGD | |
| SCHEMBL11902623 | 0.78 | ALDH1A1 (0.53) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL1686347 | 0.78 | POLB (0.66) | L3MBTL1ACRMAPTALDH1A1HPGD | |
| SCHEMBL5035527 | 0.77 | F10 (0.59) | L3MBTL1NPSR1ALDH1A1KDM4EHPGD | |
| SCHEMBL508571 | 0.77 | KMT2A (0.61) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL21523702 | 0.77 | MAPT (0.46) | L3MBTL1ACRMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-B1 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMA INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |