⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964941 | 0.84 | — | — | |
| SCHEMBL12807536 | 0.82 | GPR84 (0.47) | — | |
| SCHEMBL11078546 | 0.82 | GPR84 (0.47) | — | |
| SCHEMBL10613218 | 0.81 | — | — | |
| SCHEMBL965751 | 0.80 | GPR84 (0.50) | — | |
| SCHEMBL6554143 | 0.80 | GPR84 (0.50) | — | |
| SCHEMBL964723 | 0.80 | GPR84 (0.50) | — | |
| SCHEMBL965155 | 0.80 | GPR84 (0.50) | — | |
| SCHEMBL19711749 | 0.80 | GPR84 (0.50) | — | |
| SCHEMBL963283 | 0.80 | GPR84 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922564-B | Trimerization catalysts from sterically hindered salts and tertiary amines having isocyanate-reactive groups | 赢创运营有限公司 | 2021-10-19 | — | — | CN | claimed |
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | claimed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-05-02 | — | — | US | disclosed |
| EP-2536716-B1 | AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-05-21 | — | — | EP | disclosed |
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
| US-20070142413-A1 | Pyrazole derivatives as inhibitors of receptor tyrosone kinases | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | US | disclosed |
| CN-1210264-C | 1,3-dialkyl-2-imidazolinones and its prepn. | MITSUI CHEMICALS INC (JP) | 2005-07-13 | — | — | CN | disclosed |
| EP-0992497-B1 | Manufactoring process for 1,3-Dialkyl-2-imidazolinones | MITSUI CHEMICALS INC (JP) | 2003-12-17 | — | — | EP | disclosed |
| US-6492528-B1 | 1,3-DIALKYL-2-IMIDAZOLIDINONES IN A DIRECT ONE-STEP REACTION FROM INDUSTRIALLY AVAILABLE ALKYLENE CARBONATE, N-ALKYLETHANOLAMINE OR 1,2-DIOL, WHICH CAN MINIMIZE FORMING SOLID MATERIALS AND BE READILY CONDUCTED IN AN INDUSTRIAL | MITSUI CHEMICALS, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1148052-A2 | 1,3-dialkyl-2-imidazolidinones and a manufacturing process therefor | Mitsui Chemicals, Inc. (JP) | 2001-10-24 | — | — | EP | disclosed |
| EP-1148051-A2 | 1,3-dialkyl-2-imidazolidinones and a manufacturing process therefor | Mitsui Chemicals, Inc. (JP) | 2001-10-24 | — | — | EP | disclosed |
| CN-1256268-A | 1,3-dialkyl-2-imidazolinones and its prepn. | MITSUI CHEMICALS INC (JP) | 2000-06-14 | — | — | CN | disclosed |
| EP-0992497-A1 | 1,3-Dialkyl-2-imidazolidinones and a manufacturing process therefor | Mitsui Chemicals, Inc. (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0912693-A2 | DETERGENT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043391-A2 | DETERGENT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-20 | — | — | WO | disclosed |