Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.64 |
| ▸ | PPARD | Q03181 | 8/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 12/20 | 0.60 |
| ▸ | NR1H3 | Q13133 | 12/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055211 | 0.94 | NR1H3 (0.65) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4065858 | 0.92 | NR1H3 (0.66) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4063594 | 0.91 | NR1H3 (0.65) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4064059 | 0.91 | NR1H3 (0.62) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4052861 | 0.89 | NR1H2 (0.57) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4063625 | 0.87 | PPARG (0.63) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4054594 | 0.86 | PPARG (0.65) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4065495 | 0.85 | PPARG (0.60) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4059815 | 0.85 | PPARG (0.62) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL4054337 | 0.83 | NR1H2 (0.49) | PPARGPPARDPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689389-A4 | INDOLE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-06-17 | — | — | EP | disclosed |
| EP-1689389-A2 | INDOLE COMPOUNDS | National Health Research Institutes (TW) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005056522-A2 | INDOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-06-23 | — | — | WO | disclosed |