Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465843 | 0.88 | MEN1 (0.62) | MEN1KMT2ATP53LMNASMN1; SMN2 | |
| SCHEMBL1465115 | 0.86 | SMN1; SMN2 (0.65) | MEN1KMT2ATP53LMNASMN1; SMN2 | |
| SCHEMBL1463649 | 0.81 | MAPT (0.63) | MEN1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL4066714 | 0.78 | CNR2 (0.57) | MEN1KMT2ATP53LMNASMN1; SMN2 | |
| SCHEMBL4071291 | 0.74 | CNR2 (0.46) | TP53LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL1465183 | 0.74 | CNR2 (0.78) | MEN1KMT2ASMN1; SMN2CNR2CNR1 | |
| SCHEMBL4570740 | 0.73 | SMN1; SMN2 (0.57) | MEN1KMT2ATP53LMNASMN1; SMN2 | |
| SCHEMBL1464658 | 0.72 | CNR2 (0.71) | MEN1KMT2APOLBCNR2CNR1 | |
| SCHEMBL1465768 | 0.71 | CNR2 (0.59) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL8550596 | 0.71 | NTRK1 (0.65) | MEN1KMT2ATP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |