Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 17/20 | 0.59 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065069 | 0.81 | EGLN1 (0.41) | EGLN3EGLN1EGLN2 | |
| SCHEMBL2087702 | 0.77 | EGLN1 (0.71) | EGLN3EGLN1EGLN2 | |
| SCHEMBL3422298 | 0.77 | EGLN3 (0.64) | EGLN3EGLN1EGLN2 | |
| SCHEMBL338012 | 0.76 | EGLN1 (0.66) | EGLN3EGLN1EGLN2 | |
| SCHEMBL1640566 | 0.76 | EGLN3 (0.79) | EGLN3EGLN1EGLN2 | |
| SCHEMBL1640610 | 0.76 | EGLN3 (1.00) | EGLN3EGLN1EGLN2 | |
| SCHEMBL3422070 | 0.76 | EGLN3 (0.62) | EGLN3EGLN1EGLN2 | |
| SCHEMBL3421192 | 0.76 | EGLN3 (0.69) | EGLN3EGLN1EGLN2 | |
| SCHEMBL2088536 | 0.76 | EGLN1 (0.62) | EGLN3EGLN1EGLN2 | |
| SCHEMBL3420467 | 0.75 | EGLN3 (0.56) | EGLN3EGLN1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009039323-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | claimed |
| WO-2009039323-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009039323-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | disclosed |