Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062363 | 0.90 | MAPK14 (0.48) | MAPK14HSP90AA1HSP90AB1 | |
| SCHEMBL4396093 | 0.87 | HSP90AA1 (0.58) | MAPK14HSP90AA1HSP90AB1 | |
| SCHEMBL4057821 | 0.85 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL4071820 | 0.79 | P2RX3 (0.49) | MAPK14 | |
| SCHEMBL28701261 | 0.79 | MAPK14 (0.49) | MAPK14HSP90AA1HSP90AB1 | |
| SCHEMBL28934605 | 0.79 | HSP90AA1 (0.45) | MAPK14HSP90AA1HSP90AB1 | |
| SCHEMBL28701252 | 0.79 | HSP90AA1 (0.45) | MAPK14HSP90AA1HSP90AB1 | |
| SCHEMBL28701259 | 0.78 | HSP90AA1 (0.44) | MAPK14HSP90AA1HSP90AB1 | |
| SCHEMBL4065970 | 0.77 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1 | |
| SCHEMBL28702727 | 0.77 | MAPK14 (0.46) | MAPK14HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |