Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897406 | 0.86 | TP53 (0.57) | TP53RECQLOPRL1ADRA1AADRA1B | |
| Charcoal, Activated SCHEMBL5897477 | 0.84 | TP53 (0.55) | TP53RECQLOPRL1ADRA1AADRA1B | |
| SCHEMBL3789653 | 0.82 | TP53 (0.53) | TP53RECQLOPRL1ADRA1AADRA1B | |
| SCHEMBL3784740 | 0.82 | TP53 (0.53) | TP53RECQLOPRL1ADRA1AADRA1B | |
| SCHEMBL2316090 | 0.80 | TP53 (0.52) | TP53RECQLOPRL1ADRA1AADRA1B | |
| SCHEMBL5406701 | 0.78 | DPP4 (0.49) | TP53RECQLOPRL1ADRA1AADRA1B | |
| SCHEMBL8747411 | 0.77 | TP53 (0.53) | TP53RECQLOPRL1TRPV6HTR2A | |
| SCHEMBL11832831 | 0.77 | TP53 (0.48) | TP53RECQLOPRL1ADRA1AADRA1B | |
| SCHEMBL20178459 | 0.77 | OPRL1 (0.59) | TP53RECQLOPRL1ADRA1AADRA1B | |
| SCHEMBL11444228 | 0.77 | TP53 (0.48) | TP53RECQLOPRL1ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| CN-1538956-A | Spiro compounds | ������ҩ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |