SCHEMBL406513

SCHEMBL406513

Cc1cccc(N)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28802800 0.85 TDP1 (0.45)
SCHEMBL31257532 0.83
SCHEMBL130382 0.80
SCHEMBL928091 0.80
SCHEMBL29781768 0.80 CYP3A4 (0.48)
SCHEMBL19208273 0.80 CYP3A4 (0.48)
SCHEMBL1425839 0.76 CYP3A4 (0.40)
SCHEMBL30839716 0.75 CD44 (0.65)
SCHEMBL3462069 0.75 CD44 (0.65)
SCHEMBL16934069 0.72 ACHE (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-115850103-B Preparation method of 3-amino-2-fluorobenzoic acid methyl ester 北京颖泰嘉和生物科技股份有限公司 2023-04-28 CN claimed
CN-115850103-A Preparation method of 3-amino-2-fluorobenzoic acid methyl ester 北京颖泰嘉和生物科技股份有限公司 2023-03-28 CN claimed
EP-2313377-B1 METHOD FOR STEREOSELECTIVE SYNTHESIS OF BICYCLIC HETEROCYCLES BOEHRINGER INGELHEIM INT (DE) 2016-01-06 EP claimed
US-8263768-B2 Process for the stereoselective preparation of bicyclic heterocycles BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-09-11 US claimed
US-20120116080-A1 PROCESS FOR THE STEREOSELECTIVE PREPARATION OF BICYCLIC HETEROCYCLES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-05-10 US claimed
EP-2313377-A1 METHOD FOR STEREOSELECTIVE SYNTHESIS OF BICYCLIC HETEROCYCLENE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-04-27 EP claimed
EP-2313481-A2 PRODUCTION PROCESS OF UNLEADED HIGH OCTANE NUMBER GASOLINE, AND SO OBTAINED GASOLINES CHIMEC S.P.A. (IT) 2011-04-27 EP claimed
WO-2010015524-A1 METHOD FOR STEREOSELECTIVE SYNTHESIS OF BICYCLIC HETEROCYCLENE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-02-11 WO claimed
WO-2010001341-A2 PRODUCTION PROCESS OF UNLEADED HIGH OCTANE NUMBER GASOLINE, AND SO OBTAINED GASOLINES CHIMEC S.P.A. (IT) 2010-01-07 WO claimed
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF DIFFERENTIATED THERAPEUTICS INC (US) 2026-03-12 US disclosed
US-12570631-B2 Substituted N-(4-(pyrimidin and pyridin-4-yl)benzylcarboxamides and its use for treating disorders responsive to inhibition of Btk BIOGEN MA INC. (US) 2026-03-10 US disclosed
EP-4688775-A1 SUBSTITUTED SULTAM COMPOUND DERIVATIVES AND THEIR PHARMACEUTICAL USE Avelos Therapeutics Inc. (KR) 2026-02-11 EP disclosed
EP-4665332-A2 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF Differentiated Therapeutics Inc (US) 2025-12-24 EP disclosed
EP-4652154-A1 NOVEL ALPK1 INHIBITORS Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) 2025-11-26 EP disclosed
CN-1257861-A Aniline derivs. and producing process thereof NIHON NOHYAKU CO LTD (JP) 2000-06-28 CN disclosed
EP-1006102-A2 Aniline derivative and process for producing the same NIHON NOHYAKU CO., LTD. (JP) 2000-06-07 EP disclosed
CN-1039492-C Herbicides ZENECA LTD (GB) 1998-08-12 CN disclosed
CN-1095066-A Weedicide ZENECA LTD (GB) 1994-11-16 CN disclosed
EP-0103392-A1 Fortified epoxy resin compositions and process for the preparation thereof Canadian Patents and Development Limited Société Canadienne des Brevets et d'Exploitation Limitée (CA) 1984-03-21 EP disclosed