Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.63 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184420 | 0.89 | HTR2C (0.56) | HTR2C | |
| SCHEMBL9184426 | 0.89 | HTR2C (0.56) | HTR2C | |
| SCHEMBL1847401 | 0.87 | HTR2C (0.73) | HTR2CKDM1AMAOB | |
| SCHEMBL15611355 | 0.83 | HTR2C (0.44) | HTR2CKDM1A | |
| SCHEMBL5147805 | 0.83 | HTR2C (0.68) | HTR2CKDM1A | |
| SCHEMBL2539686 | 0.83 | HTR2C (0.68) | HTR2CKDM1A | |
| SCHEMBL14888841 | 0.81 | HTR2C (0.51) | HTR2C | |
| Cyanide SCHEMBL27770959 | 0.81 | HTR2C (0.66) | HTR2CKDM1AMAOB | |
| SCHEMBL3681390 | 0.81 | HTR2C (0.66) | HTR2CKDM1A | |
| Dimethylamine SCHEMBL27903575 | 0.79 | HTR2C (0.63) | HTR2CKIF11KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| US-5380462-A | Cyclohexyl alkenoate compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-01-10 | — | — | US | disclosed |