SCHEMBL4065221

SCHEMBL4065221

CCOP(=O)(CCCn1c2ccc(C(=O)c3ccccc3C)cc2c2cc([N+](=O)[O-])ccc21)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.43
POLB P06746 1/20 0.43
ATM Q13315 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
CNR2 P34972 2/20 0.41
ELANE P08246 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HTT P42858 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PSEN1 P49768 1/20 0.38
PSEN2 P49810 1/20 0.38
APH1B Q8WW43 1/20 0.38
NCSTN Q92542 1/20 0.38
APH1A Q96BI3 1/20 0.38
PSENEN Q9NZ42 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15930035 0.90 MAPT (0.42) MAPTPOLBATMMEN1KMT2A
SCHEMBL4065224 0.90 MAPT (0.42) MAPTPOLBATMMEN1KMT2A
SCHEMBL4070536 0.90 MAPT (0.42) MAPTPOLBATMMEN1KMT2A
SCHEMBL4067881 0.88 MAPT (0.39) MAPTPOLBATMMEN1KMT2A
SCHEMBL4062431 0.85 MAPT (0.44) MAPTPOLBATMMEN1KMT2A
SCHEMBL4062361 0.83 MAPT (0.61) MAPTPOLBATMMEN1KMT2A
SCHEMBL4063017 0.82 MAPT (0.43) MAPTPOLBATMMEN1KMT2A
SCHEMBL15930036 0.82 MAPT (0.41) MAPTPOLBATMMEN1KMT2A
SCHEMBL4065144 0.81 MAPT (0.50) MAPTPOLBATMMEN1KMT2A
SCHEMBL15930038 0.80 KMT2A (0.41) MAPTPOLBATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168369-B2 Photoactive compound and photosensitive resin composition containing the same LG CHEM, LTD. (KR) 2012-05-01 US disclosed
US-20110318692-A1 PHOTOACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE SAME LG CHEM, LTD. (KR) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110318692-A1 PHOTOACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE SAME CCNT1, RFT1, SULT1A1 MAPT 96/4885POLB 2409/4885ATM 916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.