⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cytosine SCHEMBL28686892 | 0.98 | DYRK1A (0.41) | — | |
| Cytosine SCHEMBL1330710 | 0.98 | — | — | |
| Cytosine SCHEMBL4059 | 0.98 | — | — | |
| Cytosine SCHEMBL4657334 | 0.98 | DYRK1A (0.44) | — | |
| Cytosine SCHEMBL1330400 | 0.98 | — | — | |
| Cytosine SCHEMBL19692377 | 0.95 | — | — | |
| Cytosine SCHEMBL10623341 | 0.95 | — | — | |
| Cytosine SCHEMBL2406920 | 0.95 | — | — | |
| Cytosine SCHEMBL21772310 | 0.95 | DYRK1A (0.42) | — | |
| Cytosine SCHEMBL4492966 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102206240-B | Process for the synthesis of azacitidine and decitabine | CHEMI SPA | 2015-01-21 | — | — | CN | claimed |
| CN-102206240-A | Process for the synthesis of azacitidine and decitabine | CHEMI SPA | 2011-10-05 | — | — | CN | claimed |
| CN-118974277-A | Nucleic acid amplification with higher exponential radix than radix 2 using high and low Tm primers | 赛沛公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-117982528-A | Application of schisandra chinensis polysaccharide in preparation of medicines for relieving DSS-induced ulcerative colitis of mice | 江苏农牧科技职业学院 | 2024-05-07 | — | — | CN | disclosed |
| CN-105246918-B | Growth hormone secretagogue receptor related protein, nucleic acid, preparation method and application thereof | 王庆华 | 2019-11-05 | — | — | CN | disclosed |
| CN-109526222-A | 5' -cyclic phosphonate modified nucleotide | 箭头药业股份有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-107260690-A | Lyophilized formulations of Decitabine and preparation method thereof | 江苏豪森药业集团有限公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-106661579-A | Methods and compositions for preventing ischemia-reperfusion injury in an organ | 夸克制药公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-101473045-B | Methods and compositions for detecting autoimmune disorders | 健泰科生物技术公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-105327363-A | Immunostimulatory oligonucleotides | SELECTA BIOSCIENCES INC | 2016-02-17 | — | — | CN | disclosed |
| CN-103347542-B | Immunostimulatory oligonucleotides | SELECTA BIOSCIENCES, INC. (US) | 2015-09-16 | — | — | CN | disclosed |
| CN-1777363-A | beta-L-2' -deoxynucleosides for the treatment of resistant HBV strains and combination therapy | IDENIX CAYMAN LTD (KY) | 2006-05-24 | — | — | CN | disclosed |
| CN-1745089-A | immunostimulatory sequence oligonucleotides and methods of use | DYNAVAX TECHNOLOGIES (US) | 2006-03-08 | — | — | CN | disclosed |
| EP-1594882-A1 | PROCESS FOR PREPARING BRANCHED RIBONUCLEOSIDES FROM 1, 2-ANHYDRORIBOFURANOSE INTERMEDIATES | Merck & Co., Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| CN-1674878-A | Immunomodulatory compositions, methods of making, and methods of use thereof | DYNAVAX TECH CORP (US) | 2005-09-28 | — | — | CN | disclosed |
| US-20050158770-A1 | Microwave mediated synthesis of nucleic acid probes | VENTANA MEDICAL SYSTEMS, INC. (US) | 2005-07-21 | — | — | US | disclosed |
| WO-2005064018-A2 | MICROWAVE MEDIATED SYNTHESIS OF NUCLEIC ACID PROBES | VENTANA MEDICAL SYSTEMS, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| WO-2004072090-A1 | PROCESS FOR PREPARING BRANCHED RIBONUCLEOSIDES FROM 1, 2-ANHYDRORIBOFURANOSE INTERMEDIATES | MERCK & CO. INC. (US) | 2004-08-26 | — | — | WO | disclosed |
| CN-1392153-A | Process for prparing cytidine compound | MITSUBISHI CHEM IND (JP) | 2003-01-22 | — | — | CN | disclosed |
| CN-1352696-A | Adipose-derived stem cells and grids | UNIV PITTSBURGH (US) | 2002-06-05 | — | — | CN | disclosed |