SCHEMBL4065553

SCHEMBL4065553

O=C1C=CC(c2ccccc2)=CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 2/20 0.37
GOPC Q9HD26 2/20 0.37
LMNA P02545 2/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
ALDH1A1 P00352 3/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
MGLL Q99685 2/20 0.32
FAAH O00519 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
PLA2G10 O15496 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PARL Q9H300 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6408186 0.84 ALDH1A1 (0.37) LMNAMAPTHTTALDH1A1KMT2A
SCHEMBL7108660 0.76 HDAC4 (0.31) HDAC4HDAC2HDAC8PARL
SCHEMBL19834896 0.76 ALDH1A1 (0.35) ALDH1A1
SCHEMBL27852135 0.74 ALDH1A1 (0.33) ALDH1A1
SCHEMBL20553971 0.74 ALDH1A1 (0.33) LMNAALDH1A1
SCHEMBL23499902 0.74
SCHEMBL29607560 0.74
SCHEMBL2999133 0.72 AXL (0.34) CFTRGOPCLMNAMAPTHTT
SCHEMBL28445481 0.72 KMT2A (0.32) CFTRGOPCLMNAMAPTHTT
SCHEMBL9099387 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286588-A Process for preparing pentamethylene isocyanurate 中海油常州涂料化工研究院有限公司 2022-11-04 CN claimed
WO-2022126647-A1 HIGH-TEMPERATURE ENERGY STORAGE HYBRID POLYETHERIMIDE DIELECTRIC THIN FILM, PREPARATION METHOD THEREFOR AND USE THEREOF 清华大学 2022-06-23 WO claimed
US-7488517-B2 Method of producing porous nitrile rubber coated indoor athletic socks WHANG BRIAN 2009-02-10 US claimed
EP-1748754-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE SPECIFIC BLOCK COPOLYMER L'OREAL (FR) 2007-02-07 EP claimed
WO-2005110351-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE SPECIFIC BLOCK COPOLYMER L'OREAL (FR) 2005-11-24 WO claimed
EP-0002104-B1 PLEOCHROIC DYES SUITABLE FOR USE IN SOLUTION WITH LIQUID CRYSTAL MATERIALS FOR ELECTRO-OPTIC DEVICE APPLICATIONS BDH Chemicals Limited (GB) 1982-10-20 EP claimed
CN-115286588-B Process for the preparation of pentamethylene isocyanurate 中海油常州涂料化工研究院有限公司 2024-07-09 CN disclosed
CN-118215704-A Method for promoting hydrosilylation reactions to produce ester-functional siloxane oligomers 陶氏环球技术有限责任公司 2024-06-18 CN disclosed
CN-112334520-B Polyamide resin film and resin laminate using same 株式会社LG化学 2024-04-02 CN disclosed
CN-110709774-B Underlayer film forming material, resist underlayer film, method for producing resist underlayer film, and laminate 三井化学株式会社 2023-12-08 CN disclosed
CN-115745842-B Method for synthesizing aromatic carbamate by photocatalysis 华南理工大学 2023-10-20 CN disclosed
CN-113207294-B Polymer resin composition, and polymer film and resin laminate using same 株式会社LG化学 2023-10-20 CN disclosed
CN-112243448-B Polyamide resin, and polymer film and resin laminate using same 株式会社LG化学 2023-07-25 CN disclosed
EP-0025143-B1 MORTARS FROM INORGANIC BINDERS, PROCESS FOR THEIR PRODUCTION AND THEIR USE BAYER AG (DE) 1983-01-26 EP disclosed
EP-0002104-B1 PLEOCHROIC DYES SUITABLE FOR USE IN SOLUTION WITH LIQUID CRYSTAL MATERIALS FOR ELECTRO-OPTIC DEVICE APPLICATIONS BDH Chemicals Limited (GB) 1982-10-20 EP disclosed
US-4327018-A Azo dyes and the production and use thereof CIBA-GEIGY CORPORATION (US) 1982-04-27 US disclosed
EP-0025143-A1 Mortars from inorganic binders, process for their production and their use BAYER AG (DE) 1981-03-18 EP disclosed
US-4254255-A Aqueous reaction of polyamine with alkylene dihalide in presence of emulsifier BAYER AKTIENGESELLSCHAFT (DE) 1981-03-03 US disclosed
EP-0011814-A1 Process for dyeing mixtures of polyester and wool BAYER AG (DE) 1980-06-11 EP disclosed
EP-0003499-A1 Process for the manufacture of water-soluble condensation products, their use in papermaking and process-aids containing these condensation products BAYER AG (DE) 1979-08-22 EP disclosed