Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405661 | 1.00 | EPHX1 (0.36) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25936685 | 0.85 | SIGMAR1 (0.41) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14629009 | 0.85 | SIGMAR1 (0.41) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL463616 | 0.85 | SIGMAR1 (0.41) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14621087 | 0.85 | SIGMAR1 (0.41) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL463655 | 0.85 | SIGMAR1 (0.41) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14598858 | 0.85 | SIGMAR1 (0.41) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12793731 | 0.80 | KCNH2 (0.43) | KCNH2SMN1; SMN2ALDH1A1MAOBKMT2A | |
| SCHEMBL6562226 | 0.77 | KCNH2 (0.38) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6561474 | 0.75 | KCNH2 (0.38) | EPHX1KCNH2SIGMAR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120064002-A1 | Enantiomer-pure (4S,8S)- and (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triaza-3N,6N,9N-tricarboxymethyl-1,11-undecanedioic Acid and Derivatives Thereof, Process for their Production and Use for the Production of Pharmaceutical Agents | LEHMANN LUTZ (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064002-A1 | Enantiomer-pure (4S,8S)- and (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triaza-3N,6N,9N-tricarboxymethyl-1,11-undecanedioic Acid and Derivatives Thereof, Process for their Production and Use for the Production of Pharmaceutical Agents | CYP4B1, CYP2B6, UGT2B7 | EPHX1 1790/4885KCNH2 2726/4885SIGMAR1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.