Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | GAA | P10253 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | CLK1 | P49759 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.67 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MMP14 | P50281 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060137 | 0.89 | MAPT (0.82) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL4059114 | 0.87 | MAPT (1.00) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL4285556 | 0.81 | CLK1 (0.63) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL4064388 | 0.81 | CLK1 (0.63) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL4063265 | 0.80 | CLK1 (1.00) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL30697294 | 0.80 | CLK1 (1.00) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL4288409 | 0.78 | ALDH1A1 (0.73) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL4288413 | 0.78 | ALDH1A1 (0.73) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL4062708 | 0.78 | CLK1 (0.93) | MAPTGAATDP1KDM4ECLK1 | |
| SCHEMBL4241354 | 0.77 | ALDH1A1 (0.49) | MAPTGAATDP1KDM4ECLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |