SCHEMBL4066786

SCHEMBL4066786

CCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.81
ITGB3 P05106 2/20 0.65
ITGA2B P08514 2/20 0.65
PSMB5 P28074 2/20 0.64
HDAC3 O15379 1/20 0.60
HDAC4 P56524 1/20 0.60
HDAC1 Q13547 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC2 Q92769 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC8 Q9BY41 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60
HDAC5 Q9UQL6 1/20 0.60
NOD1 Q9Y239 1/20 0.58
EPHX2 P34913 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9506671 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL9716823 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL1815009 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL1815011 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL9666114 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL22494096 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL22494095 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL21998924 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL22494097 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3
SCHEMBL15285319 1.00 FAAH (0.81) FAAHITGB3ITGA2BPSMB5HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891764-A1 N-acylamino acids and cosmetics using the same KASHIMA OIL COMPANY (JP) 1999-01-20 EP claimed
JP-11080105-A None JP disclosed
EP-4662197-A1 METHOD FOR PURIFICATION OF AMINO ACID SURFACTANTS BASF SE (DE) 2025-12-17 EP disclosed
US-12194080-B2 Methods for identification, assessment, prevention, and treatment of metabolic disorders using PM20D1 and N-lipidated amino acids DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-01-14 US disclosed
WO-2024165426-A1 METHOD FOR PURIFICATION OF AMINO ACID SURFACTANTS BASF SE (DE) 2024-08-15 WO disclosed
EP-4414360-A1 METHOD FOR PURIFICATION OF AMINO ACID SURFACTANTS BASF SE (DE) 2024-08-14 EP disclosed
EP-3368157-B1 METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND TREATMENT OF METABOLIC DISORDERS USING PM20D1 AND N-LIPIDATED AMINO ACIDS DANA FARBER CANCER INST INC (US) 2022-06-29 EP disclosed
US-20210106661-A1 METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND TREATMENT OF METABOLIC DISORDERS USING PM20D1 AND N-LIPIDATED AMINO ACIDS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-04-15 US disclosed
EP-1309336-B1 DERIVATIVES OF LASPARTOMYCIN AND PREPARATION AND USE THEREOF BIOSOURCE PHARM INC (US) 2009-05-06 EP disclosed
EP-1309336-A4 DERIVATIVES OF LASPARTOMYCIN AND PREPARATION AND USE THEREOF MICROLOGIX BIOTECH INC (CA) 2005-01-05 EP disclosed
US-6737403-B2 CULTURING MICROORGANISM STREPTOMYCES VIRIDOCHROMOGENES, SSP. KOMABENSIS (ATCC 29814) IN CULTURE MEDIUM, ISOLATING LASPARTOMYCIN, CLEAVING LIPOPHILIC FRAGMENT FROM LASPARTOMYCIN, THEREBY YIELDING LASPARTOMYCIN CORE PEPTIDE MICROLOGIX BIOTECH INC. (CA) 2004-05-18 US disclosed
EP-0891764-B1 Ethanolic solutions of N-pentadecanoylisoleucine and use thereof in cosmetics KASHIMA OIL (JP) 2004-02-18 EP disclosed
EP-1309336-A1 DERIVATIVES OF LASPARTOMYCIN AND PREPARATION AND USE THEREOF Micrologix Biotech, Inc. (CA) 2003-05-14 EP disclosed
US-20020035063-A1 Derivatives of laspartomycin and preparation and use thereof BIOSOURCE PHARM, INC. 2002-03-21 US disclosed
WO-2002005838-A1 DERIVATIVES OF LASPARTOMYCIN AND PREPARATION AND USE THEREOF INTRABIOTICS PHARMACEUTICALS, INC. (US) 2002-01-24 WO disclosed
JP-H1180105-A N-ACYLAMINO ACID AND COSMETIC USING THE SAME KASHIMA SEKIYU KK 1999-03-26 JP disclosed
EP-0891764-A1 N-acylamino acids and cosmetics using the same KASHIMA OIL COMPANY (JP) 1999-01-20 EP disclosed
EP-0891764-A1 N-acylamino acids and cosmetics using the same KASHIMA OIL COMPANY (JP) 1999-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035063-A1 Derivatives of laspartomycin and preparation and use thereof VIP, LAS1L, PREP FAAH 1789/4885ITGB3 4515/4885ITGA2B 4809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.