Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | SOD1 | P00441 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626565 | 0.73 | ALDH1A1 (0.49) | DAOARPDPK1GAAMAPT | |
| SCHEMBL29373097 | 0.71 | CYP3A4 (0.53) | ARGAAMAPTTDP1FDPS | |
| SCHEMBL36019 | 0.71 | CYP3A4 (0.53) | ARGAAMAPTTDP1FDPS | |
| SCHEMBL9719138 | 0.69 | CYP3A4 (0.50) | ARGAAMAPTTDP1FDPS | |
| Hydrochloric Acid SCHEMBL11743462 | 0.69 | CYP3A4 (0.50) | ARGAAMAPTTDP1FDPS | |
| Ammonia Solution, Strong SCHEMBL9517239 | 0.69 | CYP3A4 (0.50) | ARGAAMAPTTDP1FDPS | |
| SCHEMBL1759362 | 0.69 | CYP3A4 (0.50) | ARGAAMAPTTDP1FDPS | |
| SCHEMBL10477010 | 0.68 | AR (0.46) | ARPARP1FDPS | |
| Hydrochloric Acid SCHEMBL1759361 | 0.67 | CYP3A4 (0.47) | ARGAAMAPTTDP1FDPS | |
| SCHEMBL28774780 | 0.67 | AR (0.42) | ARPDPK1PARP1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937046-A2 | SUBSTITUTED 3-BENZYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR LOWERING THE SUGAR CONTENT IN BLOOD | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-25 | — | — | EP | claimed |
| WO-1998020000-A2 | SUBSTITUTED 3-BENZYLPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-14 | — | — | WO | claimed |
| US-7632830-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2009-12-15 | — | — | US | disclosed |
| US-7632830-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2009-12-15 | — | — | US | disclosed |
| US-7632830-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2009-12-15 | — | — | US | disclosed |
| EP-1346993-B1 | LACTAM COMPOUNDS AND MEDICAL USE THEREOF | AJINOMOTO KK (JP) | 2009-10-21 | — | — | EP | disclosed |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | AJINOMOTO CO., INC. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | AJINOMOTO CO., INC. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | AJINOMOTO CO., INC. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-7326701-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2008-02-05 | — | — | US | disclosed |
| US-7326701-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2008-02-05 | — | — | US | disclosed |
| US-7326701-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2008-02-05 | — | — | US | disclosed |
| US-7153850-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-20060189597-A1 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20040048847-A1 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO. INC (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1346993-A1 | LACTAM COMPOUNDS AND MEDICINAL USE THEREOF | Ajinomoto Co., Inc. (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6451734-B1 | Substituted 3-benzylpyrazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
| EP-0937046-A2 | SUBSTITUTED 3-BENZYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR LOWERING THE SUGAR CONTENT IN BLOOD | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998020000-A2 | SUBSTITUTED 3-BENZYLPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189597-A1 | Lactam compounds and pharmaceutical use thereof | SLC2A4, SLC2A8, SLC2A1 | DAO 329/4885AR 2268/4885PDPK1 1747/4885 |
| US-20040048847-A1 | Lactam compounds and pharmaceutical use thereof | SLC2A4, SLC2A8, SLC2A1 | DAO 329/4885AR 2268/4885PDPK1 1747/4885 |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | SLC2A4, SLC2A8, SLC2A1 | DAO 329/4885AR 2268/4885PDPK1 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.