Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.73 |
| ▸ | GSK3B | P49841 | 1/20 | 0.73 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.73 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.73 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | USP14 | P54578 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4066978 | 0.85 | CLK1 (0.91) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL30697294 | 0.85 | CLK1 (1.00) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL4063265 | 0.85 | CLK1 (1.00) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL4062708 | 0.82 | CLK1 (0.93) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL4795234 | 0.78 | CLK1 (0.85) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL4066650 | 0.77 | CLK1 (0.70) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL10095238 | 0.75 | ALDH1A1 (0.67) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL5576861 | 0.75 | ALDH1A1 (0.59) | CLK1GSK3BDYRK1ACLK4DYRK1B | |
| SCHEMBL15503744 | 0.74 | POLB (1.00) | POLBHTTALDH1A1MAPTPKM | |
| SCHEMBL10095235 | 0.73 | CLK1 (0.58) | CLK1GSK3BDYRK1ACLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |