Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 17/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062105 | 0.88 | KIF11 (0.59) | KIF11KCNH2 | |
| SCHEMBL4064573 | 0.78 | KIF11 (0.70) | KIF11KCNH2 | |
| SCHEMBL4067473 | 0.78 | KIF11 (0.70) | KIF11KCNH2 | |
| SCHEMBL4060453 | 0.76 | KIF11 (0.84) | KIF11KCNH2 | |
| SCHEMBL4066223 | 0.76 | KIF11 (0.84) | KIF11KCNH2 | |
| SCHEMBL4060449 | 0.76 | KIF11 (0.84) | KIF11KCNH2 | |
| SCHEMBL4066227 | 0.76 | KIF11 (0.84) | KIF11KCNH2 | |
| SCHEMBL4057840 | 0.76 | KIF11 (0.84) | KIF11KCNH2 | |
| SCHEMBL4067640 | 0.76 | KIF11 (0.84) | KIF11KCNH2 | |
| SCHEMBL13655902 | 0.75 | KIF11 (0.70) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515724-B1 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2009-10-21 | — | — | EP | claimed |