Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450515 | 0.86 | HPGD (0.73) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL30562867 | 0.85 | HPGD (0.74) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL16353932 | 0.84 | SMN1; SMN2 (0.83) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL28478191 | 0.84 | POLB (1.00) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL23080118 | 0.83 | HPGD (0.70) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL12125320 | 0.83 | SMN1; SMN2 (0.80) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL12845344 | 0.82 | ALOX15 (0.69) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL9385223 | 0.82 | SMN1; SMN2 (1.00) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL1690435 | 0.81 | HPGD (0.68) | HPGDALOX15TDP1POLBSMN1; SMN2 | |
| SCHEMBL6665224 | 0.81 | HPGD (0.68) | HPGDALOX15TDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014111113-A1 | ACYLGUANIDINES FOR TREATING OSTEOARTHRITIS | MERCK PATENT GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| US-7060752-B2 | Synthesis and use of nitrophenol resins | NEW YORK UNIVERSITY (US) | 2006-06-13 | — | — | US | disclosed |
| US-20040087726-A1 | Synthesis and use of nitrophenol resins | NEW YORK UNIVERSITY | 2004-05-06 | — | — | US | disclosed |