Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989359 | 0.94 | MAPK14 (0.57) | MAPK14PTGESCYP2C9 | |
| SCHEMBL4061072 | 0.92 | MAPK14 (0.55) | MAPK14PTGESCYP2C9MAPTMEN1 | |
| SCHEMBL3997933 | 0.89 | MAPK14 (0.51) | MAPK14MAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL4061387 | 0.85 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL4067941 | 0.85 | PRKCQ (0.44) | MAPK14PTGESCYP2C9CYP2D6 | |
| SCHEMBL4063899 | 0.83 | MAPK14 (0.54) | MAPK14MAPTMEN1KMT2AMAPK13 | |
| SCHEMBL3992567 | 0.83 | MAPK14 (0.45) | MAPK14MAPTMEN1KMT2A | |
| SCHEMBL4122831 | 0.82 | MAPT (0.43) | MAPK14MAPTKMT2A | |
| SCHEMBL3989284 | 0.80 | MAPK14 (0.43) | MAPK14PTGESCYP2C9MAPTMAPK13 | |
| SCHEMBL4067901 | 0.80 | BRAF (0.38) | MAPK14MEN1KMT2AMAPK13RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713805-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2009-06-10 | — | — | EP | disclosed |