Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071061 | 0.74 | CLK1 (0.59) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL4066328 | 0.70 | HTT (0.56) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL4794811 | 0.68 | CLK1 (0.53) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL4066828 | 0.67 | KDM4E (0.48) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL4066826 | 0.66 | HTT (0.49) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL4066605 | 0.66 | CLK1 (0.60) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL4066957 | 0.65 | HTT (0.56) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL14627875 | 0.65 | KDM4E (0.59) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL5577123 | 0.64 | KDM4E (0.44) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL979587 | 0.61 | GRIK2 (0.52) | MAPTMEN1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |