Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066328 | 0.79 | HTT (0.56) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4066828 | 0.72 | KDM4E (0.48) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4794811 | 0.69 | CLK1 (0.53) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL25613235 | 0.69 | KDM4E (0.60) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL12109147 | 0.69 | KDM4E (0.49) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL5577123 | 0.68 | KDM4E (0.44) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL10165569 | 0.68 | EDNRA (0.50) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL31484565 | 0.67 | KDM4E (0.56) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL366921 | 0.66 | KDM4E (1.00) | HTTKDM4EMEN1KMT2AMAPT | |
| SCHEMBL9537669 | 0.66 | KDM4E (0.53) | HTTKDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |