Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066591 | 0.92 | CXCR4 (0.35) | CXCR4ITGB3ITGA2B | |
| SCHEMBL4069741 | 0.92 | CXCR4 (0.40) | CXCR4TLR9TLR7 | |
| SCHEMBL4531719 | 0.91 | CXCR4 (0.39) | CXCR4TLR9TLR7 | |
| SCHEMBL4075050 | 0.88 | CXCR4 (0.39) | CXCR4 | |
| SCHEMBL4069861 | 0.87 | CXCR4 (0.38) | CXCR4TLR9TLR7 | |
| SCHEMBL4074096 | 0.87 | CXCR4 (0.41) | CXCR4ITGB3ITGA2BGHSR | |
| SCHEMBL4072336 | 0.87 | CXCR4 (0.51) | CXCR4ITGB3ITGA2BGHSR | |
| SCHEMBL4225549 | 0.87 | CXCR4 (0.44) | CXCR4 | |
| SCHEMBL4069884 | 0.86 | CXCR4 (0.43) | CXCR4ITGB3ITGA2BGHSR | |
| SCHEMBL4069031 | 0.86 | CXCR4 (0.38) | CXCR4TLR9TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325992-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2055705-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | Ono Pharmaceutical CO., LTD. (JP) | 2009-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325992-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | CXCR4, CXCL12, CXCR1 | CXCR4 1/4885TLR9 119/4885TLR7 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.