Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233793 | 0.96 | CXCR4 (0.45) | CXCR4KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4237781 | 0.92 | CXCR4 (0.44) | CXCR4KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2626916 | 0.92 | CXCR4 (0.45) | CXCR4KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4531719 | 0.91 | CXCR4 (0.39) | CXCR4KMT2AALDH1A1MEN1HRH3 | |
| SCHEMBL4230314 | 0.91 | CXCR4 (0.43) | CXCR4KMT2AKDM4EMEN1HRH3 | |
| SCHEMBL4229078 | 0.90 | CXCR4 (0.46) | CXCR4KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2694515 | 0.90 | CXCR4 (0.44) | CXCR4KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4225603 | 0.90 | CXCR4 (0.42) | CXCR4KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4069741 | 0.90 | CXCR4 (0.40) | CXCR4KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4075050 | 0.89 | CXCR4 (0.39) | CXCR4KMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618122-B2 | Compound having acidic group which may be protected, and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-12-31 | — | — | US | disclosed |
| EP-2042503-B1 | COMPOUND HAVING ACIDIC GROUP WHICH MAY BE PROTECTED, AND USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2013-01-30 | — | — | EP | disclosed |
| US-20090192182-A1 | COMPOUND HAVING ACIDIC GROUP WHICH MAY BE PROTECTED, AND USE THEREOF | ONO PHARMACEUTICAL CO.,LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| EP-2042503-A1 | COMPOUND HAVING ACIDIC GROUP WHICH MAY BE PROTECTED, AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192182-A1 | COMPOUND HAVING ACIDIC GROUP WHICH MAY BE PROTECTED, AND USE THEREOF | CXCR4, CXCR3, CXCL12 | CXCR4 1/4885KMT2A 4124/4885ALDH1A1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.