Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.48 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898423 | 1.00 | IDO1 (0.48) | IDO1TDO2GABBR2GABBR1AOC3 | |
| SCHEMBL3252261 | 0.77 | IDO1 (0.52) | IDO1TDO2GABBR2GABBR1AOC3 | |
| SCHEMBL933502 | 0.77 | IDO1 (0.52) | IDO1TDO2GABBR2GABBR1AOC3 | |
| SCHEMBL3544057 | 0.77 | IDO1 (0.46) | IDO1TDO2AOC3HDAC3HDAC4 | |
| SCHEMBL12568800 | 0.77 | IDO1 (0.52) | IDO1TDO2GABBR2GABBR1AOC3 | |
| SCHEMBL3675765 | 0.77 | IDO1 (0.52) | IDO1TDO2AOC3HDAC3HDAC4 | |
| SCHEMBL9906118 | 0.77 | IDO1 (0.52) | IDO1TDO2GABBR2GABBR1AOC3 | |
| SCHEMBL2008053 | 0.77 | IDO1 (0.52) | IDO1TDO2GABBR2GABBR1AOC3 | |
| Hydrochloric Acid SCHEMBL14119361 | 0.74 | IDO1 (0.54) | IDO1TDO2GABBR2GABBR1AOC3 | |
| SCHEMBL21994503 | 0.74 | IDO1 (0.44) | IDO1TDO2AOC3HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409903-B2 | Benzyl substituted triazine derivatives and their therapeutical applications | NANTBIOSCIENCE, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150057285-A1 | BENZYL SUBSTITUTED TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | NANTBIOSCIENCE INC (US) | 2015-02-26 | — | — | US | disclosed |
| EP-1686999-B1 | PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES | ASTRAZENECA AB (SE) | 2009-07-01 | — | — | EP | disclosed |
| CN-1968933-A | Pyrazole derivatives useful for the treatment of cancer | ASTRAZENECA AB (SE) | 2007-05-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057285-A1 | BENZYL SUBSTITUTED TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | BAZ2A, BAZ2B, PRKCZ | IDO1 3441/4885TDO2 3991/4885GABBR2 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.