Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A4 | P14672 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065565 | 0.89 | MEN1 (0.54) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL4072842 | 0.83 | CYP1A2 (0.62) | ALDH1A1HTTCYP1A2CYP2D6 | |
| SCHEMBL4068318 | 0.83 | CYP1A2 (0.58) | ALDH1A1HTTTDP1CYP1A2CYP2D6 | |
| SCHEMBL1042566 | 0.81 | SLC2A4 (0.63) | SLC2A4ALDH1A1GAAMAPTCA9 | |
| SCHEMBL4067663 | 0.77 | CHRM2 (0.50) | ALDH1A1GAAMAPTMEN1KMT2A | |
| 4-Formylpyridine SCHEMBL25376714 | 0.74 | SLC2A4 (0.51) | SLC2A4ALDH1A1GAAMAPTHTT | |
| SCHEMBL25697049 | 0.74 | ALDH1A1 (0.46) | SLC2A4ALDH1A1GAAMAPTHTT | |
| SCHEMBL6616250 | 0.74 | MAOB (0.65) | GAAMAPTMEN1KMT2ATDP1 | |
| Pyridine SCHEMBL9737571 | 0.73 | CYP1A2 (0.61) | SLC2A4ALDH1A1GAAMAPTHTT | |
| SCHEMBL28188921 | 0.73 | GAA (0.74) | ALDH1A1GAAMAPTCA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| CN-1538956-A | Spiro compounds | ������ҩ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |