Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066049 | 0.86 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL4065674 | 0.85 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL4068253 | 0.84 | KCNH2 (0.48) | KCNH2LMNANPSR1 | |
| SCHEMBL4075361 | 0.83 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL2954817 | 0.76 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL2946555 | 0.76 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL4069052 | 0.74 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL4066322 | 0.74 | SLC2A1 (0.44) | KCNH2KDM4ELMNAGLAMAPT | |
| SCHEMBL4063525 | 0.74 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL4069048 | 0.74 | KCNH2 (0.42) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-B1 | Antibacterial derivatives of napthydrin and quinoline | GLAXO GROUP LTD (GB) | 2009-02-11 | — | — | EP | claimed |