Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3157843 | 0.85 | NPY5R (0.39) | NPY5RHCRTR2CA12CA1CA9 | |
| SCHEMBL18284064 | 0.80 | GRIA4 (0.39) | NPY5RHCRTR2CA12CA1CA9 | |
| SCHEMBL4070065 | 0.79 | HTR2C (0.42) | — | |
| SCHEMBL127018 | 0.78 | CYP11B2 (0.38) | NPY5RHCRTR2GRIA4 | |
| SCHEMBL3682231 | 0.76 | KDM1A (0.41) | — | |
| SCHEMBL23933275 | 0.75 | CA12 (0.33) | CA12CA1CA9HCAR2 | |
| SCHEMBL14295821 | 0.75 | CYP11B2 (0.39) | — | |
| SCHEMBL18721989 | 0.74 | ESR2 (0.47) | NPY5RHCRTR2GRM2GRIA4 | |
| SCHEMBL21731693 | 0.74 | ESR2 (0.48) | NPY5RHCRTR2CA12CA1CA9 | |
| SCHEMBL28695098 | 0.74 | NPY5R (0.35) | NPY5RHCRTR2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |