Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | CCKBR | P32239 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842487 | 0.87 | TACR1 (0.56) | CTSLCTSSCTSKCCKBRMAPT | |
| SCHEMBL9331123 | 0.87 | MAPT (0.55) | CTSLCTSSCTSKMAPTKDM4E | |
| SCHEMBL29571655 | 0.86 | KDM4E (0.67) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL21641794 | 0.86 | KDM4E (0.67) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL31074794 | 0.86 | KDM4E (0.67) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL10434701 | 0.86 | KDM4E (0.67) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL7824245 | 0.86 | KDM4E (0.67) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL27871958 | 0.85 | ERAP1 (0.60) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL16463539 | 0.85 | TACR1 (0.60) | CTSLCTSSCTSKMAPTTACR1 | |
| SCHEMBL16463542 | 0.85 | TACR1 (0.60) | CTSLCTSSCTSKMAPTTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309336-B1 | DERIVATIVES OF LASPARTOMYCIN AND PREPARATION AND USE THEREOF | BIOSOURCE PHARM INC (US) | 2009-05-06 | — | — | EP | disclosed |
| US-6737403-B2 | CULTURING MICROORGANISM STREPTOMYCES VIRIDOCHROMOGENES, SSP. KOMABENSIS (ATCC 29814) IN CULTURE MEDIUM, ISOLATING LASPARTOMYCIN, CLEAVING LIPOPHILIC FRAGMENT FROM LASPARTOMYCIN, THEREBY YIELDING LASPARTOMYCIN CORE PEPTIDE | MICROLOGIX BIOTECH INC. (CA) | 2004-05-18 | — | — | US | disclosed |