Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117301 | 0.77 | PRKCE (0.38) | HCAR2 | |
| SCHEMBL13727646 | 0.76 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL10429473 | 0.75 | GPR84 (0.39) | HCAR2 | |
| SCHEMBL4273865 | 0.72 | KDM4E (0.34) | — | |
| SCHEMBL10429469 | 0.71 | GPR84 (0.44) | HCAR2 | |
| SCHEMBL11581688 | 0.71 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL2115423 | 0.70 | — | — | |
| SCHEMBL2118423 | 0.70 | — | — | |
| SCHEMBL7940988 | 0.70 | GPR84 (0.51) | CHRM2CHRM5CHRM1CHRM3TSHR | |
| SCHEMBL10004688 | 0.69 | GPR84 (0.34) | HCAR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646657-A | Process for producing trichloropyrimidine compound | SUMITOMO CHEMICAL CO JP | 2010-02-10 | — | — | CN | disclosed |
| EP-2128141-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2009-12-02 | — | — | EP | disclosed |