Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755734 | 0.81 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL7819528 | 0.79 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL7598502 | 0.78 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL2785015 | 0.77 | MEN1 (0.47) | PPARG | |
| SCHEMBL5761364 | 0.75 | PPARG (0.73) | PPARGPPARAPPARD | |
| SCHEMBL5762738 | 0.74 | PPARG (0.79) | PPARGPPARAPPARD | |
| SCHEMBL5761633 | 0.74 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL7926429 | 0.73 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL6815603 | 0.72 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL5760185 | 0.72 | PPARG (0.79) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105234-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH DEFECTS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE OR PROTEIN | COMBINATORX, INCORPORATED (US) | 2009-08-27 | — | — | WO | disclosed |