Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.59 |
| ▸ | PPARA | Q07869 | 11/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068968 | 0.78 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL2785140 | 0.74 | PPARG (1.00) | PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL7705753 | 0.73 | PPARG (0.98) | PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL7705758 | 0.73 | PPARG (0.98) | PPARGPPARAPPARD | |
| SCHEMBL2785015 | 0.72 | MEN1 (0.47) | PPARG | |
| SCHEMBL5418415 | 0.67 | PPARG (0.41) | PPARGPPARA | |
| SCHEMBL5768928 | 0.67 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL4648482 | 0.67 | ELANE (0.36) | PPARG | |
| Hydrochloric Acid SCHEMBL5420491 | 0.66 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL2786718 | 0.66 | PPARG (1.00) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137794-A1 | Retinoic acid receptor (RAR) agonists, agonists for steroid/thyroid hormone receptor superfamily, and an agonist for a heterodimer partner | SALK INSTITUTE FOR BIOLOGICAL STUDIES, THE | 2002-09-26 | — | — | US | claimed |
| US-20020137794-A1 | Retinoic acid receptor (RAR) agonists, agonists for steroid/thyroid hormone receptor superfamily, and an agonist for a heterodimer partner | SALK INSTITUTE FOR BIOLOGICAL STUDIES, THE | 2002-09-26 | — | — | US | disclosed |
| US-6436993-B1 | SYNERGISTIC MIXTURES OF RETINOIC ACID RECEPTOR (RAR) ANTAGONISTS AND STEROID, THYROID OR RETINOID RECEPTOR AGONISTS SUCH AS PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS USED TO CONTROL CELLULAR PROCESSES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2002-08-20 | — | — | US | disclosed |
| WO-2001003659-A1 | USE OF RAR ANTAGONISTS AS MODULATORS OF HORMONE MEDIATED PROCESSES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2001-01-18 | — | — | WO | disclosed |