Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529852 | 0.86 | SELL (0.56) | DPP4TSHRALDH1A1SMN1; SMN2CASP1 | |
| SCHEMBL10533170 | 0.84 | SELL (0.60) | DPP4TSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL73043 | 0.82 | TSHR (0.54) | DPP4TSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL3546145 | 0.82 | SELL (0.64) | TSHRALDH1A1SMN1; SMN2CASP1KDM4E | |
| SCHEMBL30084375 | 0.82 | TSHR (0.54) | DPP4TSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL29886586 | 0.81 | TSHR (0.64) | DPP4TSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL432644 | 0.81 | TSHR (0.64) | DPP4TSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL4509639 | 0.80 | DPP4 (0.43) | DPP4TSHRALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL32690872 | 0.80 | TSHR (0.61) | TSHRALDH1A1SMN1; SMN2TP53CASP1 | |
| SCHEMBL217628 | 0.80 | TSHR (0.61) | TSHRALDH1A1SMN1; SMN2TP53CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737831-A4 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LTD (AU) | 2009-07-22 | — | — | EP | disclosed |
| EP-1737831-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | Prana Biotechnology Limited (AU) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005095360-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2005-10-13 | — | — | WO | disclosed |
| EP-0741719-A4 | INTERMEDIATE AND PROCESS FOR MAKING | LILLY CO ELI (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0741719-A1 | INTERMEDIATE AND PROCESS FOR MAKING | ELI LILLY AND COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0722439-A1 | HIV PROTEASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995021164-A1 | INTERMEDIATE AND PROCESS FOR MAKING | ELI LILLY AND COMPANY (US) | 1995-08-10 | — | — | WO | disclosed |
| US-5075497-A | Chemical intermediate for 2-(2,3,4-trisubstitutedbenzoyl)-1,3-cyclohexanedione | ICI AMERICAS, INC. (US) | 1991-12-24 | — | — | US | disclosed |
| US-5073642-A | Trisubstituted benzoic acid intermediates | ICI AMERICAS INC. (US) | 1991-12-17 | — | — | US | disclosed |
| US-5068423-A | Intermediates for herbicides 2-(2,3,4-trisubstituted benzoyl)-1,3-cyclohexanediones | ICI AMERICAS INC. (US) | 1991-11-26 | — | — | US | disclosed |
| US-5047572-A | For 2-*2,3,4-trisubstituted benzoyl)-1,3-cyclohexanedione | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |
| US-5001256-A | Trisubstituted benzoic acid intermediates | ICI AMERICAS INC. (US) | 1991-03-19 | — | — | US | disclosed |
| US-4957538-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0044205-B1 | POLYESTER OF 6-HYDROXY-2-NAPHTHOIC ACID AND METAHYDROXY BENZOIC ACID CAPABLE OF READILY UNDERGOING MELT PROCESSING | CELANESE CORPORATION (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4337190-A | Polyester of 6-hydroxy-2-naphthoic acid and meta-hydroxy benzoic acid capable of readily undergoing melt processing | CELANESE CORPORATION (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0044205-A1 | Polyester of 6-hydroxy-2-naphthoic acid and metahydroxy benzoic acid capable of readily undergoing melt processing | CELANESE CORPORATION (US) | 1982-01-20 | — | — | EP | disclosed |