SCHEMBL432644

SCHEMBL432644

O=C(O)c1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
ALDH1A1 P00352 4/20 0.52
TP53 P04637 1/20 0.52
CASP1 P29466 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CYP1A2 P05177 1/20 0.48
CSNK2A2 P19784 1/20 0.47
CSNK2B P67870 1/20 0.47
CSNK2A1 P68400 1/20 0.47
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 2/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
DPP4 P27487 1/20 0.43
LMNA P02545 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29886586 1.00 TSHR (0.64) TSHRALDH1A1TP53CASP1SMN1; SMN2
SCHEMBL27938221 0.98 TSHR (0.61) TSHRALDH1A1TP53CASP1SMN1; SMN2
SCHEMBL27553108 0.98 TSHR (0.61) TSHRALDH1A1TP53CASP1SMN1; SMN2
SCHEMBL10606007 0.98 TSHR (0.61) TSHRALDH1A1TP53CASP1SMN1; SMN2
SCHEMBL8617010 0.98 TSHR (0.61) TSHRALDH1A1TP53CASP1SMN1; SMN2
SCHEMBL32690872 0.89 TSHR (0.61) TSHRALDH1A1TP53CASP1SMN1; SMN2
SCHEMBL217628 0.89 TSHR (0.61) TSHRALDH1A1TP53CASP1SMN1; SMN2
2,3,6-Trichlorobenzoic Acid SCHEMBL9328359 0.89 TSHR (0.53) TSHRALDH1A1TP53CASP1SMN1; SMN2
SCHEMBL21582021 0.88 TSHR (0.52) TSHRALDH1A1TP53CASP1SMN1; SMN2
SCHEMBL3940987 0.83 TSHR (0.47) TSHRALDH1A1TP53CASP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 926 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025125568-A1 ENHANCED AUXIN MIMIC HERBICIDE W. NEUDORFF GMBH KG (DE) 2025-06-19 WO claimed
CN-111868015-B Intelligent release type potash fertilizer particles 瑞南科技私人有限公司 2023-12-08 CN claimed
CN-111868014-B Intelligent release type nitrogen-containing fertilizer particles 瑞南科技私人有限公司 2023-12-08 CN claimed
CN-108884018-B Dendritic polymers and formulations thereof 优星私人有限公司 2021-08-31 CN claimed
US-10981858-B2 Dendrimer and formulations thereof Priostar Pty Ltd (AU) 2021-04-20 US claimed
CN-109757479-A Complex herbicidal composition and its preparation and application containing dicamba 山东润博生物科技有限公司 2019-05-17 CN claimed
US-20180370900-A1 DENDRIMER AND FORMULATIONS THEREOF STARPHARMA PTY LTD. (AU) 2018-12-27 US claimed
CN-109042721-A Herbicidal combinations and its application 四川利尔作物科学有限公司 2018-12-21 CN claimed
CN-108935507-A Agricultural active ingredients and its application 四川利尔作物科学有限公司 2018-12-07 CN claimed
EP-3390348-A1 DENDRIMER AND FORMULATIONS THEREOF Priostar Pty Ltd (AU) 2018-10-24 EP claimed
WO-1994023018-A1 IMMUNOASSAY FOR TETRACHLOROISOPHTHALONITRILE (CHLOROTHALONIL®), ITS DERIVATIVES AND BREAKDOWN PRODUCTS ISK BIOSCIENCES CORPORATION (US) 1994-10-13 WO claimed
EP-0596015-A1 SUBSTITUTED BETA-LACTAM COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS AND PROCESSES FOR THE PREPARATION THEREOF. SCHERING CORP (US) 1994-05-11 EP claimed
US-5266553-A Nuetralization of carboxylic acid salt RIVERDALE CHEMICAL COMPANY (US) 1993-11-30 US claimed
US-5185471-A Reacting 5-halo-2-nitrobenzotrifluorides with inorganic base to form 1,1*-oxy-Bis(3-trifluoromethyl-4-nitrobenzen using benzoate catalyst OCCIDENTAL CHEMICAL CORPORATION (US) 1993-02-09 US claimed
WO-1993002048-A1 SUBSTITUTED BETA-LACTAM COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS AND PROCESSES FOR THE PREPARATION THEREOF SCHERING CORPORATION (US) 1993-02-04 WO claimed
EP-0524595-A1 Substituted beta-lactam compounds useful as hypocholesterolemic agents and processes for the preparation thereof SCHERING CORPORATION (US) 1993-01-27 EP claimed
CN-1044206-A Improved glyphosate formulation MONSANTO CO (US) 1990-08-01 CN claimed
WO-1990006975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1990-06-28 WO claimed
US-4111684-A A BENZOIC ACID CELANESE CORPORATION (US) 1978-09-05 US claimed
US-4106926-A CONTROLLED RELEASE OF BENZOIC ACID DERIVATIVE CELANESE CORPORATION (US) 1978-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10981858-B2 Dendrimer and formulations thereof DDT, PDCD2L, DNM2 TSHR 2610/4885ALDH1A1 683/4885TP53 542/4885
US-20180370900-A1 DENDRIMER AND FORMULATIONS THEREOF DDT, PDCD2L, DNM2 TSHR 2610/4885ALDH1A1 683/4885TP53 542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.