Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.57 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 4/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581428 | 1.00 | CCR1 (0.57) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL4063723 | 0.89 | CCR1 (0.54) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL4061000 | 0.88 | CCR1 (0.48) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL7581508 | 0.88 | CCR1 (0.56) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL4065574 | 0.88 | CCR1 (0.56) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL4059666 | 0.88 | CCR1 (0.56) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL6836076 | 0.88 | CCR1 (0.56) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL2675868 | 0.87 | CCR1 (0.48) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL2675827 | 0.87 | CCR1 (0.48) | CCR1SLC15A1CSNK1ELAP3ANPEP | |
| SCHEMBL4071838 | 0.85 | CCR1 (0.45) | CCR1SLC15A1CSNK1ELAP3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966443-B1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR | PFIZER (US) | 2009-01-28 | — | — | EP | disclosed |